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What is the Bufo Experience?

Bufo alvarius, also known as Otac, is a toad that lives in Northern Mexico. The toad produces a milky secretion that contains 5-MeO-DMT, a tryptamine that is naturally occurring in the human brain and is referred to as the "God Molecule."

Bufo comes from the Seri, an indigenous group in the Sonoran Desert. The use of 5-MeO-DMT can be traced back thousands of years from different plant and animal sources that many cultures used as a direct connection to God.

Our mind is coherent with the world, and when we do not repress the intuitions that link us with other people and with nature, we can become aware of our oneness with the Universe.

- James Oroc, The Tryptamine Palace: 5-MeO-DMT and the Sonoran Desert Toad

Typically, during the ceremony the secretion from the toad is vaporized and inhaled. Bufo experience can last anywhere from 20 minutes to over an hour, depending on dosage administered and the individual’s ability to retain the vapour.


While the approach to each person is individual, the first dose is usually a lower "Harmony Dose" to allow you to enter into the vibration of the medicine, which then may be followed by a higher dose.


After Bufo is administered, often people describe the experience as the consciousness leaving the body and the person enters the space of "everything and nothing."


The experience brings upon the remembrance of your true self and connection to the divine.

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